tag:blogger.com,1999:blog-24021163.post6104334933986529898..comments2024-02-18T01:56:38.508-06:00Comments on M.D.O.D.: Family Möbius Strip911DOChttp://www.blogger.com/profile/06466669111561150174noreply@blogger.comBlogger45125tag:blogger.com,1999:blog-24021163.post-61666634634645353322008-08-24T14:17:00.000-05:002008-08-24T14:17:00.000-05:00As one who lives below the Mason Dixon line, I ass...As one who lives below the Mason Dixon line, I assure you this is NOT Southbashing. It could not in fact happen just anywhere. There's a reason why Deliverance was not filmed in Delaware.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-71367249334278367792008-08-16T21:40:00.000-05:002008-08-16T21:40:00.000-05:00Hey I'm sorry we all went overboard with the unecc...Hey I'm sorry we all went overboard with the uneccessary Southern US bashing. It was all in good humour, with no ill intent and no aim to stereotype anyone. This is a one-off incident which could have happened anywhere.<BR/><BR/>At the same time, I'm glad that you found some humour in it, no matter how dark or perverse. I hope this blog can retain its sharp, nearly caustic humour.. instead of being politically correct and running the risk of sounding boring!TheAbacushttps://www.blogger.com/profile/08055048810673583429noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-67179403428576436482008-08-16T20:53:00.000-05:002008-08-16T20:53:00.000-05:00Hi Teresa! I know, I know - I think I came off as...Hi Teresa! I know, I know - I think I came off as a little/a lot more sensitive than I am in reality. I really do know where Etotheipi is coming from and loved the post. Just wanted to try and give him a little bit of a hard time. I have to admit, I am actually related to toothless hillbillies (by marriage, of course haha)who live in the Ozarks - but we absolutely have no inbreeding in our family. I am proud to be southern and wouldn't live anywhere else. I got quite a chuckle out of your joke, by the way!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-44570825770472857612008-08-16T18:33:00.000-05:002008-08-16T18:33:00.000-05:00We're not all toothless hillbillies!Dear Dr. Pedim...<I>We're not all toothless hillbillies!</I><BR/><BR/>Dear Dr. Pedimom,<BR/><BR/>Ahem. Well, actually, I was born in the Ozarks, in Arkansas, and raised in the south. I may be a hillbilly, and I definitely am 25% toothless, but this post doesn't bother me. In some sense I am still very much a hillbilly hick, in spite of the fact that I am hyper-educated and a classically trained musician. I am not ashamed of my southern, very rural roots. Don't let this stuff get to ya.<BR/><BR/><I>I've got to hand it to you yanks and San Fran types- you gave us Teddy K, John "rambo" Kerry, Nancy "angry botox grandma" Pelosi, gay marriage, high taxes, tree huggers...</I><BR/><BR/>See, now there's the right attitude.<BR/><BR/>And à propos of this post, I'll leave you with this joke:<BR/><BR/><I>Q: What do Yankees and sperm have in common? <BR/>A: One in 3,000,000 has a chance of becoming a human being.</I><BR/><BR/>Love, TeresaHey, Youhttps://www.blogger.com/profile/16677869087980832387noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-70546822939493610572008-08-16T17:17:00.000-05:002008-08-16T17:17:00.000-05:00OK - Maybe I am being overly sensitive, but does a...OK - Maybe I am being overly sensitive, but does anyone else think the south is getting a bad rap here! I grew up in the south(as did my husband - S.Cat) and it has produced some pretty remarkable people (and NO I'm not including the Clintons). Also, I did my pediatric residency at Arkansas Children's Hospital (ranked in the top 25 Children's Hospitals in America by U.S. News and World Report)and never did I have a patient that remotely resembled this f'd up shit on E's genetic diagram. We're not all toothless hillbillies! Etotheipi, I love you man but this is harsh!! I've got to hand it to you yanks and San Fran types- you gave us Teddy K, John "rambo" Kerry, Nancy "angry botox grandma" Pelosi, gay marriage, high taxes, tree huggers (love those guys-they make me laugh), maple syrup, and a host of other great stuff. <BR/><BR/>Wife O' CatAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-6505433580578112032008-08-16T12:05:00.000-05:002008-08-16T12:05:00.000-05:00For math humor go to: http://dinosaurmusings.blo...For math humor go to: <BR/><BR/> http://dinosaurmusings.blogspot.com/<BR/><BR/>(The tune is "I Will Survive", the lyrics are "I Will Derive")Devorrahhttps://www.blogger.com/profile/14542045173559671539noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-23754256067195167652008-08-16T09:53:00.000-05:002008-08-16T09:53:00.000-05:00teresa:A+My calculations exactly.Igloodoc:The hono...teresa:<BR/>A+<BR/>My calculations exactly.<BR/><BR/>Igloodoc:<BR/>The honorable mention stands.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-17820070039649263472008-08-16T00:53:00.000-05:002008-08-16T00:53:00.000-05:00dear lilly,we never meant to bring joy but damn......dear lilly,<BR/>we never meant to bring joy but damn... we'll humbly accept that thank you.<BR/>cheers911DOChttps://www.blogger.com/profile/06466669111561150174noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-70448923901814408572008-08-15T23:34:00.000-05:002008-08-15T23:34:00.000-05:00may i just THANK YOU for the joy your blog has bro...may i just THANK YOU for the joy your blog has brought a small group of us in the er.<BR/>we love it...<BR/>i mean you just know us so well!!Unknownhttps://www.blogger.com/profile/14432477563187010259noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-64888499859695243932008-08-15T20:36:00.000-05:002008-08-15T20:36:00.000-05:00This comment has been removed by the author.Hey, Youhttps://www.blogger.com/profile/16677869087980832387noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-81077305241386425722008-08-15T20:15:00.000-05:002008-08-15T20:15:00.000-05:00This comment has been removed by the author.Amelia Ameshttps://www.blogger.com/profile/17296224743117560163noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-5595793798969748762008-08-15T19:02:00.000-05:002008-08-15T19:02:00.000-05:00Umm... this is a very complex problem that has bee...Umm... this is a very complex problem that has been the subject of genetics papers.<BR/><BR/><BR/>There are approx 30,000 genes in the human genome. Simple sexual reproduction says that half of the DNA of the offspring is from the father, so 50% of the genes are shared by the father. (not counting mitochondrial DNA, which always comes from the mother)<BR/><BR/> Now, as to how many genes are expressed the same as the father... this depends on how many of the father's genes and mother's genes are dominant vs recessive.<BR/>It also depends on mutations, crossovers and incomplete gene expression, and X linked traits. The genome project estimates that 6.7 % of the genome is heterozygous, or about 2100 genes are heterozygous. The remaining genes are homozygous and are static (and breed true).<BR/><BR/> Just look at the genetics of 2 genes. If heterozygous genes A and B are mated (or in other words AaBb mates AaBb), the expression of the genes is a ratio of <BR/><BR/>9 Dominant both genes (AxBx): <BR/>3 Dominant A recessive b (Axbb): <BR/>3 Dominant B recessive a (aaBx):<BR/>1 Recessive (aabb)<BR/><BR/>This is just 2 genes.<BR/><BR/>The father is capable of producing 2^2100 different combinations of the 2100 genes. Same with the mother. Without knowing the father's genotype, you assume that half are dominant (which in an inbreeding situation is a wrong assumption). The postulated formulas are really complex. Suffice it to say that if the human genome has 6.7% heterozygous genes, the the inbred child will have less than 6.7% heterozygous genes.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-12086208497418409442008-08-15T18:01:00.000-05:002008-08-15T18:01:00.000-05:00all grandparents of the 1st generation are unrelat...<I>all grandparents of the 1st generation are unrelated. </I><BR/><BR/>I meant, of course, unrelated to their spouses. Clearly given that the 1st generation are cousins, 2 of the grandparents are more than just related, they are the same people.<BR/><BR/>Oh, and I forgot to add my signature.<BR/><BR/>Love, TeresaHey, Youhttps://www.blogger.com/profile/16677869087980832387noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-78240826971183951442008-08-15T17:50:00.000-05:002008-08-15T17:50:00.000-05:00OK, Dr. etotheipi, here's what I get. Please grad...OK, Dr. etotheipi, here's what I get. Please grade my work leniently, bearing in mind that I am not a medical doctor.<BR/><BR/>I am assuming that genes from unrelated individuals are 0% shared, and that all grandparents of the 1st generation are unrelated. <BR/><BR/>1st generation couple have 25% common genes.<BR/><BR/>2nd generation is a brother and sister, children of the cousins above. They share 62.5% in common.<BR/><BR/>Their child shares 81.25% with each of her parents.<BR/><BR/>The child of this girl's union with her father, your patient, shares 90.625% with her father. 50% she gets directly from her father. The other 50% she gets from her mother, who has in common 81.25% with her father/bed-partner/freak. Therefore, 81.25% of the (50%) genes she gets from her mother are in common with her father, or 40.625% of the total, making her 50% + 40.625% = 90.625% genetically identical to her father (on average). <BR/><BR/>Hmmmm, maybe cloning isn't as hard as I thought.Hey, Youhttps://www.blogger.com/profile/16677869087980832387noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-10212278395926406552008-08-15T15:28:00.000-05:002008-08-15T15:28:00.000-05:00Ok, I don't have all the answers but I have one re...Ok, I don't have all the answers but I have one real answer for #6 (some poor girl/victim actually said this)<BR/><BR/>"Daddy, I think you popped my cherry."<BR/><BR/>And yes, this was in the south...Significant Snailhttps://www.blogger.com/profile/16524718962850001779noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-63017334322653536542008-08-15T13:45:00.000-05:002008-08-15T13:45:00.000-05:00Why don't you post your calculation? Maybe that wi...Why don't you post your calculation? Maybe that will clear things out a bit..TheAbacushttps://www.blogger.com/profile/08055048810673583429noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-28957197391057900872008-08-15T13:43:00.000-05:002008-08-15T13:43:00.000-05:00It's a bit over 90%. Try again.It's a bit over 90%. Try again.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-85336265044024133622008-08-15T13:20:00.000-05:002008-08-15T13:20:00.000-05:00Holy crap! I took out my calculator and some ondan...Holy crap! I took out my calculator and some ondansetron to try and work this one out. Turns out I got the <I>exact same figure</I> as Teresa. Well, almost. I've also taken into account the 1st cousin aspects etc. Wow.. hats off to you! Took me ages..<BR/><BR/>The numbers we have crunched are just theoretical, as these are just general averages. Interestingly, the part of the genetic code which actually varies between people, which accounts for one's phenotype, is minuscule. Turns out the average genetic variation between Adolf Hitler, Barbara Streisand, Helen Keller, Michael Jackson and YOU is 0.1%. Scary thought. And to think that variations in this 0.1% give rise to the variety of people which inhabit this planet, amazing!<BR/><BR/>http://en.wikipedia.org/wiki/Human_genetic_variation<BR/><BR/>As a fitting end to this discussion, I'd like to quote a small dialogue from House..<BR/><BR/>Dr. Gregory House: Oxygen saturation is 94 percent. Check her heart.<BR/>Dr. Eric Foreman: Her oxygen saturation is normal.<BR/>Dr. Gregory House: It's off by one percentage point.<BR/>Dr. Eric Foreman: It's within range. It's normal.<BR/>Dr. Gregory House: If her DNA was off by one percentage point, she'd be a dolphin.<BR/><BR/>Ah.. classic stuff.TheAbacushttps://www.blogger.com/profile/08055048810673583429noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-11032682228873769112008-08-15T12:16:00.000-05:002008-08-15T12:16:00.000-05:00etotheipiMy therapist wants me to thank you for th...etotheipi<BR/>My therapist wants me to thank you for the honorable mention.<BR/><BR/>My wife, however, says it is justification for locking me in the basement whenever I am not supervised. Again.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-4835187333081582802008-08-15T10:50:00.000-05:002008-08-15T10:50:00.000-05:00Dear Dr. etotheipi,Actually, I didn't forget to in...Dear Dr. etotheipi,<BR/><BR/>Actually, I didn't forget to include the 1st cousin aspect, but you are right, I am wrong. I stumbled at the end over my own vomit. Maybe later I can try again, when I have some time. I do so wanna be teacher's pet.<BR/><BR/>Love, TeresaHey, Youhttps://www.blogger.com/profile/16677869087980832387noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-13551743652190687152008-08-15T10:31:00.000-05:002008-08-15T10:31:00.000-05:00Great line, Etotheipi. Wow, I suddenly feel less ...Great line, Etotheipi. Wow, I suddenly feel less nerdy.Devorrahhttps://www.blogger.com/profile/14542045173559671539noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-74103528947436695652008-08-15T10:25:00.000-05:002008-08-15T10:25:00.000-05:00teresa:I don't think you considered that the fathe...teresa:<BR/>I don't think you considered that the father's parents were first cousins... show me your math and I'll show you mine ;)Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-24021163.post-36966071750125670982008-08-15T09:58:00.000-05:002008-08-15T09:58:00.000-05:00The heck with the flow chart. I'm just gorked out ...The heck with the flow chart. I'm just gorked out with the whole story. Talk about swiss-chard-for-brains... I need a shower.Lynn Pricehttps://www.blogger.com/profile/02958402288888144904noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-39008528172368494572008-08-15T09:56:00.000-05:002008-08-15T09:56:00.000-05:00Well why don't you tell us how you got that magica...Well why don't you tell us how you got that magical number? I'm sure it will be of some help.. to me at least.TheAbacushttps://www.blogger.com/profile/08055048810673583429noreply@blogger.comtag:blogger.com,1999:blog-24021163.post-20911934954598529972008-08-15T09:52:00.000-05:002008-08-15T09:52:00.000-05:00I get ~90%. Any genetics / math whiz please tell m...<I>I get ~90%. Any genetics / math whiz please tell me if I'm wrong.</I><BR/><BR/>Well you're close. I believe the actual answer is 81.25%. I wasn't guessing at this, I calculated it. But my calculations could be wrong.<BR/><BR/><BR/><I>Now for the awards: theabacus and teresa tie for first</I><BR/><BR/>Thanks for the award! <BR/><BR/>I think.Hey, Youhttps://www.blogger.com/profile/16677869087980832387noreply@blogger.com